2D Peak Lists of Orthogonal and Tilted Planes and Their Corresponding 3D Peak List Indexes

 

 

ADAPT-NMR provides 2D peak lists for all orthogonal and tilted planes collected for each of the following the experiments:

HNCO, HN(CO)CA, HNCA, HNCB, CBCA(CO)NH, and HN(CA)CO

 

The example shown here represents a portion of the 22o plane peak list for CBCA(CO)NH experiment from the RI-Brazzein protein.

The first column and the last column are the 2d_peak_id and the most probable corresponding 3d_peak_id.  They are used to link 2D peaks with 3D peaks, and are particularly useful for any post-processing edition including manual edition of peak picking and assignment. ADAPT-NMR Enhancer, a comprehensive visualization and edition tool for ADAPT-NMR will intensively use these attributes.

w1 and w2 columns represent the position of the peaks in the 2D plane for 1H, and the mixture of 13C/ 15N respectively. Notice that because the second dimension is a linear mixture of 15N and 13C, presentation of these values in ppm is meaningless and therefor raw data point values from the spectra are reported.

The Height column represents the intensity of the peak in 2D spectra.

The Priority is an ADAPT-NMR scale for 2D peaks based on the intensity. Priority 1 is most probably a real peak, priority 2 is less probable, and priority 3 is the least probable to be a real peak vs. noise or artifact.

Notice that 90 degree tilted planes are basically 15N-HSQC experiment.

 

2d_peak_id    w1     w2     Height   Priority   3d_peak_id

 

       1     368   556.7   111371.6      1        38

       2     272   390.4    89279.6      1       326

       3     254   295.7    87745.2      1       439

       4     185   309.1    85806.6      1       404

       5     273   447.7    84519.5      1       213

       6     249   310.4    78846.4      1        56

       7     368   294.4    76482.0      1        39

       8     334   312.1    73630.0      1        14

       9     162   277.6    73185.7      1       325

      10     294   255.2    69714.9      1       437

      11     240   489.5    68472.1      1       130

      12     343   178.8    64399.0      1        36

      13     334   250.9    62455.1      1        67

      14     388   284.3    59794.4      1        72

...

...

...

     115     296   285.6     6050.4      3       421

     116     244   227.5     5941.5      3       422

     117     337   661.4     5802.3      3       224

     118     286   304.3     5646.7      3       445

     119     236   260.6     5598.0      3         0

     120     337   429.7     5365.4      3         0

     121     395   802.7     5259.4      3       424

     122     279   367.0     5137.5      3       426